CTBS Gene Summary [Human]

Chitobiase is a lysosomal glycosidase involved in degradation of asparagine-linked oligosaccharides on glycoproteins (Aronson and Kuranda, 1989 [PubMed 2531691]).[supplied by OMIM, Nov 2010]

Details

Type
Protein Coding
Official Symbol
CTBS
Official Name
chitobiase [Source:HGNC Symbol;Acc:HGNC:2496]
Ensembl ID
ENSG00000117151
Bio databases IDs NCBI: 1486 Ensembl: ENSG00000117151
Aliases chitobiase, di-N-acetylchitobiase
Synonyms 2210401K11RIK, chitobiase, CTB, Image:789813
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CTBS often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • chitinase
  • GH18_chitinase-like
  • glycosylase
  • enzyme

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • prostate cancer
  • epithelial cancer
  • adenoid cystic carcinoma
regulated by
regulates
  • chitin
  • oligosaccharide
  • hemoglobin
role in cell
  • abnormal morphology
  • function

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cell surface
  • lysosome
  • plasma

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human CTBS gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • chitin catabolic process
  • oligosaccharide catabolic process

Cellular Component

Where in the cell the gene product is active
  • extracellular space
  • lysosome

Molecular Function

What the gene product does at the molecular level
  • chitinase activity
  • chitin binding

Gene-Specific Assays for Results You Can Trust

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