MOB1B Gene Summary [Human]
The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Details
| Type | Protein Coding |
| Official Symbol | MOB1B |
| Official Name | MOB kinase activator 1B [Source:HGNC Symbol;Acc:HGNC:29801] |
| Ensembl ID | ENSG00000173542 |
| Bio databases IDs | |
| Aliases | MOB kinase activator 1B, Mob4A protein |
| Synonyms | 1110003E08Rik, B230364F10, MATS2, MOB4A, MOB kinase activator 1B, MOBKL1A |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MOB1B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein kinase activator
- kinase binding
- kinase activator
- protein binding
- Mob1/phocein family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MOB1B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of protein phosphorylation
- hippo signaling cascade
- regulation of protein autophosphorylation
Cellular Component
Where in the cell the gene product is active
- nucleus
- extracellular vesicular exosome
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- kinase activator activity
- protein binding
- protein serine/threonine kinase activator activity
- metal ion binding
- protein kinase activator activity
- kinase binding