SLC35B1 Gene Summary [Human]
This gene encodes a nucleotide sugar transporter which is a member of solute carrier family 35. The transporters in this family are highly conserved hydrophobic proteins with multiple transmembrane domains. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Details
| Type | Protein Coding |
| Official Symbol | SLC35B1 |
| Official Name | solute carrier family 35 member B1 [Source:HGNC Symbol;Acc:HGNC:20798] |
| Ensembl ID | ENSG00000121073 |
| Bio databases IDs | |
| Aliases | solute carrier family 35 member B1, ATP/ADP exchanger in the ER membrane |
| Synonyms | AXER, LOC287642, solute carrier family 35 member B1, solute carrier family 35, member B1, UDP galactose transporter related isozyme 1, Ugalt2, UGTREL1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLC35B1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- UDP-galactose transporter
- UAA transporter family
- protein binding
- ATP/ADP antiporter
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- Endoplasmic Reticulum
- endoplasmic reticulum membrane
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SLC35B1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- UDP-glucose transport
- UDP-galactose transmembrane transport
- ATP transport
- ADP transport
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- intracellular membrane-bounded organelle
- Golgi membrane
Molecular Function
What the gene product does at the molecular level
- UDP-galactose transmembrane transporter activity
- protein binding
- ATP:ADP antiporter activity
- UDP-glucose transmembrane transporter activity