Slc35b1 Gene Summary [Mouse]

Predicted to enable ATP:ADP antiporter activity; UDP-galactose transmembrane transporter activity; and UDP-glucose transmembrane transporter activity. Predicted to be involved in UDP-galactose transmembrane transport. Predicted to be located in nucleoplasm. Predicted to be active in Golgi membrane and endoplasmic reticulum membrane. Is expressed in jaw; metanephros; primary sex cord; skeleton; and submandibular gland primordium. Orthologous to human SLC35B1 (solute carrier family 35 member B1). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Slc35b1
Official Name
solute carrier family 35, member B1 [Source:MGI Symbol;Acc:MGI:1343133]
Ensembl ID
ENSMUSG00000020873
Bio databases IDs NCBI: 110172 Ensembl: ENSMUSG00000020873
Aliases solute carrier family 35, member B1
Synonyms AXER, LOC287642, solute carrier family 35 member B1, solute carrier family 35, member B1, UDP galactose transporter related isozyme 1, Ugalt2, UGTREL1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc35b1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • UDP-galactose transporter
  • UAA transporter family
  • protein binding
  • ATP/ADP antiporter
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • progressive familial intrahepatic cholestasis type 1
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • intracellular membrane-bounded organelle
  • Endoplasmic Reticulum
  • endoplasmic reticulum membrane
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Slc35b1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • UDP-glucose transport
  • UDP-galactose transmembrane transport
  • ATP transport
  • ADP transport

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • intracellular membrane-bounded organelle
  • Golgi membrane

Molecular Function

What the gene product does at the molecular level
  • UDP-galactose transmembrane transporter activity
  • protein binding
  • ATP:ADP antiporter activity
  • UDP-glucose transmembrane transporter activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.