RAB9B Gene Summary [Human]
This gene encodes a member of a subfamily of RAS small guanosine triphosphate (GTP)-binding proteins that regulate membrane trafficking. The encoded protein may be involved in endosome-to-Golgi transport. [provided by RefSeq, Jan 2010]
Details
| Type | Protein Coding |
| Official Symbol | RAB9B |
| Official Name | RAB9B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:14090] |
| Ensembl ID | ENSG00000123570 |
| Bio databases IDs | |
| Aliases | RAB9B, member RAS oncogene family |
| Synonyms | 9330195C02RIK, RAB9B, member RAS oncogene family, RAB9L, RGD1562951 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RAB9B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Small GTPase of the Ras superfamily (ill-defined subfamily)
- Ras family
- small monomeric GTPase
- 50S ribosome-binding GTPase
- protein binding
- identical protein binding
- Ras subfamily of RAS small GTPases
- small GTP-binding protein domain
- GDP binding
- Rab subfamily of small GTPases
- Ras of Complex, Roc, domain of DAPkinase
- Rho (Ras homology) subfamily of Ras-like small GTPases
- P-loop containing Nucleoside Triphosphate Hydrolases
Pathways
Biological processes and signaling networks where the RAB9B gene in human plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
- secretory granule membrane
- cytosol
- phagosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RAB9B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- Rab protein signal transduction
- protein transport
- retrograde transport, endosome to Golgi
Cellular Component
Where in the cell the gene product is active
- secretory granule membrane
- phagocytic vesicle
- late endosome
- cytosol
- phagocytic vesicle membrane
- plasma membrane
- lysosome
Molecular Function
What the gene product does at the molecular level
- GTP binding
- identical protein binding
- protein binding
- GTPase activity
- GDP binding