SBSN Gene Summary [Human]
Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SBSN |
| Official Name | suprabasin [Source:HGNC Symbol;Acc:HGNC:24950] |
| Ensembl ID | ENSG00000189001 |
| Bio databases IDs | |
| Aliases | suprabasin |
| Synonyms | 1110005D19Rik, RGD1562305, SUPRABASIN, UNQ698 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SBSN often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- head and neck neoplasia
- organismal death
regulates
- NFkB (complex)
- IKBKG
role in cell
- signaling in
- K63 polyubiquitination in
- Met1 linked ubiquitination in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SBSN gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome