ELOF1 Gene Summary [Human]
Predicted to enable RNA polymerase II complex binding activity. Predicted to be involved in epigenetic maintenance of chromatin in transcription-competent conformation and transcription elongation from RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of transcription elongation factor complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ELOF1 |
| Official Name | elongation factor 1 homolog [Source:HGNC Symbol;Acc:HGNC:28691] |
| Ensembl ID | ENSG00000130165 |
| Bio databases IDs | |
| Aliases | elongation factor 1 homolog, elongation factor 1 |
| Synonyms | 1110011K10Rik, ELF1, ELF1 homolog, elongation factor 1, elongation factor 1, LOC686668, RGD1309855 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ELOF1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding activity, bridging
- enzyme binding
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- chromosome
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ELOF1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- transcription elongation from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- transcription elongation factor complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- RNA polymerase II core binding