PNCK Gene Summary [Human]
PNCK is a member of the calcium/calmodulin-dependent protein kinase family of protein serine/threonine kinases (see CAMK1; MIM 604998) (Gardner et al., 2000 [PubMed 10673339]).[supplied by OMIM, Mar 2008]
Details
| Type | Protein Coding |
| Official Symbol | PNCK |
| Official Name | pregnancy up-regulated nonubiquitous CaM kinase [Source:HGNC Symbol;Acc:HGNC:13415] |
| Ensembl ID | ENSG00000130822 |
| Bio databases IDs | |
| Aliases | pregnancy up-regulated nonubiquitous CaM kinase |
| Synonyms | BSTK3, CaMK1b, CaMKIbeta2, caMKlb1, CaMKlb2, LOC100360379, pregnancy up-regulated nonubiquitous CaM kinase, pregnancy upregulated non-ubiquitously expressed CaM kinase, Punc |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PNCK often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- Serine/Threonine protein kinases, catalytic domain
- protein serine/threonine kinase
- Protein kinase (unclassified specificity)
- Protein Kinases, catalytic domain
- Protein tyrosine and serine/threonine kinase
- Protein kinase domain
- calmodulin regulated protein kinase
- Tyrosine kinase, catalytic domain
Pathways
Biological processes and signaling networks where the PNCK gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PNCK gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- peptidyl-serine phosphorylation
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- intracellular
Molecular Function
What the gene product does at the molecular level
- ATP binding
- calmodulin binding
- calmodulin-dependent protein kinase activity