Pnck Gene Summary [Mouse]
Predicted to enable calcium/calmodulin-dependent protein kinase activity and calmodulin binding activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PNCK (pregnancy up-regulated nonubiquitous CaM kinase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pnck |
| Official Name | pregnancy upregulated non-ubiquitously expressed CaM kinase [Source:MGI Symbol;Acc:MGI:1347357] |
| Ensembl ID | ENSMUSG00000002012 |
| Bio databases IDs | |
| Aliases | pregnancy upregulated non-ubiquitously expressed CaM kinase |
| Synonyms | BSTK3, CaMK1b, CaMKIbeta2, caMKlb1, CaMKlb2, LOC100360379, pregnancy up-regulated nonubiquitous CaM kinase, pregnancy upregulated non-ubiquitously expressed CaM kinase, Punc |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pnck often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- Serine/Threonine protein kinases, catalytic domain
- protein serine/threonine kinase
- Protein kinase (unclassified specificity)
- Protein Kinases, catalytic domain
- Protein tyrosine and serine/threonine kinase
- Protein kinase domain
- calmodulin regulated protein kinase
- Tyrosine kinase, catalytic domain
Pathways
Biological processes and signaling networks where the Pnck gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pnck gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- peptidyl-serine phosphorylation
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- intracellular
Molecular Function
What the gene product does at the molecular level
- ATP binding
- calmodulin binding
- calmodulin-dependent protein kinase activity