SPATA6 Gene Summary [Human]

Predicted to enable myosin light chain binding activity. Predicted to be involved in motile cilium assembly and spermatogenesis. Predicted to be located in extracellular region. Predicted to be active in sperm connecting piece. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
SPATA6
Official Name
spermatogenesis associated 6 [Source:HGNC Symbol;Acc:HGNC:18309]
Ensembl ID
ENSG00000132122
Bio databases IDs NCBI: 54558 Ensembl: ENSG00000132122
Aliases spermatogenesis associated 6, spermatogenesis-related factor-1
Synonyms 1700062C23Rik, HASH, KRP, Mash, spermatogenesis associated 6, SRF-1
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SPATA6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • myosin binding
  • protein binding
  • Spermatogenesis-assoc protein 6

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • spontaneous preterm birth
  • Parkinson disease
  • ovarian carcinoma
  • epithelial ovarian cancer
role in cell
  • assembly

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human SPATA6 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • spermatogenesis
  • cell differentiation
  • motile cilium assembly

Cellular Component

Where in the cell the gene product is active
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • myosin light chain binding

Gene-Specific Assays for Results You Can Trust

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