Spata6 Gene Summary [Mouse]
Enables myosin light chain binding activity. Involved in motile cilium assembly and spermatogenesis. Located in sperm head-tail coupling apparatus. Is expressed in several structures, including adipose tissue; central nervous system; genitourinary system; gut; and liver and biliary system. Orthologous to human SPATA6 (spermatogenesis associated 6). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Spata6 |
| Official Name | spermatogenesis associated 6 [Source:MGI Symbol;Acc:MGI:1915196] |
| Ensembl ID | ENSMUSG00000034401 |
| Bio databases IDs | |
| Aliases | spermatogenesis associated 6 |
| Synonyms | 1700062C23Rik, HASH, KRP, Mash, spermatogenesis associated 6, SRF-1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Spata6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- myosin binding
- protein binding
- Spermatogenesis-assoc protein 6
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Spata6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spermatogenesis
- cell differentiation
- motile cilium assembly
Cellular Component
Where in the cell the gene product is active
- extracellular region
Molecular Function
What the gene product does at the molecular level
- myosin light chain binding