UTP3 Gene Summary [Human]
Enables RNA binding activity. Predicted to be involved in brain development and maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | UTP3 |
| Official Name | UTP3 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:24477] |
| Ensembl ID | ENSG00000132467 |
| Bio databases IDs | |
| Aliases | UTP3 small subunit processome component, disrupter of silencing 10 |
| Synonyms | 2400011K09Rik, CRL1, CRLZ1, SAS10, UTP3 small subunit processome component, UTP3, small subunit processome component |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human UTP3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Sas10/Utp3/C1D family
- protein binding
- Sas10 C-terminal domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- pre-ribosome
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human UTP3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
- ribosomal small subunit biogenesis
- brain development
- chromatin organization
Cellular Component
Where in the cell the gene product is active
- small-subunit processome
- nucleus
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding