Utp3 Gene Summary [Rat]
Predicted to enable glutathione peroxidase activity and glutathione transferase activity. Predicted to be involved in cellular oxidant detoxification and leukotriene metabolic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum and nuclear envelope. Orthologous to human MGST3 (microsomal glutathione S-transferase 3). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Utp3 |
| Official Name | UTP3, small subunit processome component [Source:RGD Symbol;Acc:1308540] |
| Ensembl ID | ENSRNOG00000003599 |
| Bio databases IDs | |
| Aliases | UTP3, small subunit processome component |
| Synonyms | 2400011K09Rik, CRL1, CRLZ1, SAS10, UTP3 small subunit processome component, UTP3, small subunit processome component |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Utp3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Sas10/Utp3/C1D family
- protein binding
- Sas10 C-terminal domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- pre-ribosome
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Utp3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
- ribosomal small subunit biogenesis
- brain development
- chromatin organization
Cellular Component
Where in the cell the gene product is active
- small-subunit processome
- nucleus
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding