RNF17 Gene Summary [Human]
This gene is similar to a mouse gene that encodes a testis-specific protein containing a RING finger domain. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, May 2010]
Details
| Type | Protein Coding |
| Official Symbol | RNF17 |
| Official Name | ring finger protein 17 [Source:HGNC Symbol;Acc:HGNC:10060] |
| Ensembl ID | ENSG00000132972 |
| Bio databases IDs | |
| Aliases | ring finger protein 17, spermatogenesis associated 23 |
| Synonyms | MMIP-2, ring finger protein 17, SPATA23, TDRD4 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RNF17 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Tudor domain
- Protein present in Fab1, YOTB, Vac1, and EEA1
- PHD finger superfamily
- identical protein binding
- Tudor domain superfamily
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- gout
- ischemic stroke
- azoospermia
role in cell
- apoptosis
- focus formation
- focus formation in
- transformation
- development
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- perinuclear region
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RNF17 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spermatid development
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- metal ion binding