PRRG4 Gene Summary [Human]
Enables WW domain binding activity. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | PRRG4 |
| Official Name | proline rich and Gla domain 4 [Source:HGNC Symbol;Acc:HGNC:30799] |
| Ensembl ID | ENSG00000135378 |
| Bio databases IDs | |
| Aliases | proline rich and Gla domain 4 |
| Synonyms | 9930111I18Rik, LOC100506702, PRGP4, proline rich and Gla domain 4, proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane), RGD1560542, TMG4 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PRRG4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- WW domain binding
- protein binding
- Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- mammary neoplasm
- metastasis
- breast carcinoma
- inguinal hernia
role in cell
- migration
- activation in
- invasion by
- binding in
- ubiquitination in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PRRG4 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular space
- membrane
- plasma membrane
- endoplasmic reticulum-Golgi intermediate compartment membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- calcium ion binding
- WW domain binding