Mphosph6 Gene Summary [Rat]
Predicted to be involved in maturation of 5.8S rRNA. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be part of nuclear exosome (RNase complex). Orthologous to human MPHOSPH6 (M-phase phosphoprotein 6). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mphosph6 |
| Official Name | M phase phosphoprotein 6 [Source:RGD Symbol;Acc:1591222] |
| Ensembl ID | ENSRNOG00000050087 |
| Bio databases IDs | |
| Aliases | M phase phosphoprotein 6 |
| Synonyms | 1110001M01Rik, M-phase phosphoprotein 6, MPP, MPP-6 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mphosph6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- M-phase phosphoprotein 6
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- cytosol
- nucleoplasm
- nucleoli
- exosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Mphosph6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of 5.8S rRNA
Cellular Component
Where in the cell the gene product is active
- nuclear exosome (RNase complex)
- nucleus
- cytosol
- nucleolus
- nucleoplasm
- exosome (RNase complex)
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding