KCTD3 Gene Summary [Human]
This gene encodes a member of the potassium channel tetramerization-domain containing (KCTD) protein family. Members of this protein family regulate the biophysical characteristics of ion channels. In mouse, this protein interacts with hyperpolarization-activated cyclic nucleotide-gated channel complex 3 and enhances its cell surface expression and current density. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Details
| Type | Protein Coding |
| Official Symbol | KCTD3 |
| Official Name | potassium channel tetramerization domain containing 3 [Source:HGNC Symbol;Acc:HGNC:21305] |
| Ensembl ID | ENSG00000136636 |
| Bio databases IDs | |
| Aliases | potassium channel tetramerization domain containing 3 |
| Synonyms | 4930438A20RIK, 9330185B06, E330032J19Rik, NY-REN-45, potassium channel tetramerisation domain containing 3, potassium channel tetramerization domain containing 3, Ren-45 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human KCTD3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Broad-Complex, Tramtrack and Bric a brac
- BTB_POZ
- protein binding
- ion channel
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human KCTD3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein homooligomerization
Cellular Component
Where in the cell the gene product is active
- plasma membrane