NRM Gene Summary [Human]
The protein encoded by this gene contains transmembrane domains and resides within the inner nuclear membrane, where it is tightly associated with the nucleus. This protein shares homology with isoprenylcysteine carboxymethyltransferase enzymes. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
Details
| Type | Processed Transcript |
| Official Symbol | NRM |
| Official Name | nurim [Source:HGNC Symbol;Acc:HGNC:8003] |
| Ensembl ID | ENSG00000137404 |
| Bio databases IDs | |
| Aliases | nurim |
| Synonyms | 2610307M02RIK, NRM29, nurim, nurim (nuclear envelope membrane protein) |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NRM often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- inner nuclear membrane
- nuclear envelope
- nuclear lamina
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human NRM gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nuclear envelope
- nuclear inner membrane
- nuclear membrane
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding