IFI44L Gene Summary [Human]
Predicted to enable GTP binding activity. Involved in defense response to virus. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | IFI44L |
| Official Name | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] |
| Ensembl ID | ENSG00000137959 |
| Bio databases IDs | |
| Aliases | interferon induced protein 44 like |
| Synonyms | C1orf29, GS3686, H-28, H28-1, HISTOCOMPATIBILITY 28, IFI44L1, interferon-induced protein 44-like, LOC100129349, LOC100503218, NS1178, TLDC5B |
| Species | Human, Homo sapiens |
| Orthologies |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- COVID-19
- systemic lupus erythematosus
- prostate cancer
- multisystem inflammatory syndrome in children
- HER2 negative hormone receptor negative breast cancer
- psoriasis
- diabetes mellitus
- febrile seizure
- hyperzincemia and hypercalprotectinemia autoinflammatory syndrome
- uterine leiomyoma
role in cell
- response by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human IFI44L gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- immune response
- defense response to virus
Cellular Component
Where in the cell the gene product is active
- cytoplasm