IFI44 Gene Summary [Human]
Predicted to be involved in immune response. Predicted to act upstream of or within response to bacterium. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | IFI44 |
| Official Name | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] |
| Ensembl ID | ENSG00000137965 |
| Bio databases IDs | |
| Aliases | interferon induced protein 44, TBC/LysM-associated domain containing 5 |
| Synonyms | INTERFERON INDUCED protein 44, MTAP44, p44, TLDC5 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human IFI44 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- COVID-19
- cutaneous T-cell lymphoma
- peripheral T-cell lymphoma
- T-cell non-Hodgkin disease
- skin cancer
- epithelial thyroid cancer
- squamous-cell carcinoma
- pemphigus foliaceus
- mature T-cell neoplasia
- anaplastic thyroid cancer
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human IFI44 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- response to bacterium
- immune response
- response to virus
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding