SAT2 Gene Summary [Human]
Enables diamine N-acetyltransferase activity and identical protein binding activity. Involved in polyamine metabolic process. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Retained Intron |
| Official Symbol | SAT2 |
| Official Name | spermidine/spermine N1-acetyltransferase family member 2 [Source:HGNC Symbol;Acc:HGNC:23160] |
| Ensembl ID | ENSG00000141504 |
| Bio databases IDs | |
| Aliases | spermidine/spermine N1-acetyltransferase family member 2, diamine N-acetyltransferase 2 |
| Synonyms | 2610016A03Rik, spermidine/spermine N1-acetyl transferase 2, spermidine/spermine N1-acetyltransferase family member 2, SSAT-2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SAT2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Acetyltransferase (GNAT) family
- N-acetyltransferase
- NAT_SF
- Acetyltransferase (GNAT) domain
- diamine N-acetyltransferase
- enzyme
- protein binding
- identical protein binding
- ribosomal-protein-alanine acetyltransferase
Pathways
Biological processes and signaling networks where the SAT2 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SAT2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spermidine acetylation
- polyamine biosynthetic process
- nor-spermidine metabolic process
- spermine acetylation
- putrescine acetylation
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- diamine N-acetyltransferase activity
- N-acetyltransferase activity