Sat2 Gene Summary [Rat]

Predicted to enable diamine N-acetyltransferase activity and identical protein binding activity. Predicted to be involved in polyamine metabolic process. Orthologous to human SAT2 (spermidine/spermine N1-acetyltransferase family member 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Sat2
Official Name
spermidine/spermine N1-acetyltransferase family member 2 [Source:RGD Symbol;Acc:1307869]
Ensembl ID
ENSRNOG00000011714
Bio databases IDs NCBI: 360547 Ensembl: ENSRNOG00000011714
Aliases spermidine/spermine N1-acetyltransferase family member 2
Synonyms 2610016A03Rik, spermidine/spermine N1-acetyl transferase 2, spermidine/spermine N1-acetyltransferase family member 2, SSAT-2
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Sat2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Acetyltransferase (GNAT) family
  • N-acetyltransferase
  • NAT_SF
  • Acetyltransferase (GNAT) domain
  • diamine N-acetyltransferase
  • enzyme
  • protein binding
  • identical protein binding
  • ribosomal-protein-alanine acetyltransferase

Pathways

Biological processes and signaling networks where the Sat2 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • ductal breast carcinoma
  • ductal breast cancer
regulated by
  • SOAT1
  • Sertoli cells
  • epithelial cells
regulates
  • HIF1A
  • spermidine
  • spermine

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Sat2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • spermidine acetylation
  • polyamine biosynthetic process
  • nor-spermidine metabolic process
  • spermine acetylation
  • putrescine acetylation

Cellular Component

Where in the cell the gene product is active
  • extracellular vesicular exosome
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • protein binding
  • diamine N-acetyltransferase activity
  • N-acetyltransferase activity

Gene-Specific Assays for Results You Can Trust

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