IRAK1BP1 Gene Summary [Human]
Predicted to be involved in I-kappaB kinase/NF-kappaB signaling. Predicted to be located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | IRAK1BP1 |
| Official Name | interleukin 1 receptor associated kinase 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17368] |
| Ensembl ID | ENSG00000146243 |
| Bio databases IDs | |
| Aliases | interleukin 1 receptor associated kinase 1 binding protein 1 |
| Synonyms | 4921528N06Rik, Aabp3, AIP70, interleukin-1 receptor-associated kinase 1 binding protein 1, SIMPL |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human IRAK1BP1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding activity, bridging
- protein binding
- Protein of unknown function (DUF541)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human IRAK1BP1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- immune response
- positive regulation of I-kappaB kinase/NF-kappaB cascade
- I-kappaB kinase/NF-kappaB cascade
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- signaling adaptor activity