GOLGA7 Gene Summary [Human]
Involved in Golgi to plasma membrane protein transport; peptidyl-L-cysteine S-palmitoylation; and protein stabilization. Acts upstream of or within Golgi to plasma membrane transport. Located in Golgi membrane and Golgi stack. Is intrinsic component of Golgi membrane. Part of palmitoyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | GOLGA7 |
| Official Name | golgin A7 [Source:HGNC Symbol;Acc:HGNC:24876] |
| Ensembl ID | ENSG00000147533 |
| Bio databases IDs | |
| Aliases | golgin A7 |
| Synonyms | C130038N16RIK, GCP16, GOLGA3AP1, GOLGA7A, golgin A7, HSPC041 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GOLGA7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Golgin subfamily A member 7/ERF4 family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi-enriched fraction
- membrane fraction
- Extracellular Space
- organelle lumens
- Golgi Apparatus
- Golgi membrane
- Golgi stacks
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human GOLGA7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- peptidyl-L-cysteine S-palmitoylation
- Golgi to plasma membrane transport
- Golgi to plasma membrane protein transport
- protein stabilization
- protein targeting to membrane
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- Golgi membrane
- extracellular region
- Golgi stack
- palmitoyltransferase complex
Molecular Function
What the gene product does at the molecular level
- protein binding