SURF6 Gene Summary [Human]
This gene encodes a conserved protein that is localized to the nucleolus. The encoded protein may function as a nucleolar-matrix protein with nucleic acid-binding properties. There is a pseudogene for this gene on chromosome Y. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Details
| Type | Protein Coding |
| Official Symbol | SURF6 |
| Official Name | surfeit 6 [Source:HGNC Symbol;Acc:HGNC:11478] |
| Ensembl ID | ENSG00000148296 |
| Bio databases IDs | |
| Aliases | surfeit 6, surfeit locus protein 6 |
| Synonyms | D2Wsu129e, RRP14, surfeit 6, surfeit gene 6 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SURF6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Surfeit locus protein 6
- protein binding activity, bridging
- protein binding
- DNA binding
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- granular components
- chromosome
- nucleoplasm
- nucleoli
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SURF6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ribosomal large subunit biogenesis
- ribosomal small subunit biogenesis
Cellular Component
Where in the cell the gene product is active
- granular component
- chromosome
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- RNA binding
- protein binding