GPATCH11 Gene Summary [Human]

Predicted to enable nucleic acid binding activity. Located in kinetochore. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
GPATCH11
Official Name
G-patch domain containing 11 [Source:HGNC Symbol;Acc:HGNC:26768]
Ensembl ID
ENSG00000152133
Bio databases IDs NCBI: 253635 Ensembl: ENSG00000152133
Aliases G-patch domain containing 11, centromere protein Y
Synonyms 2310002B06Rik, CCDC75, CENP-Y, FLJ38348, G-patch domain containing 11, RGD1311424
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GPATCH11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-patch domain
  • Domain of unknown function (DUF4187)
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • latent tuberculosis
regulated by
  • Influenza A virus (A/Japan/305/57(H2N2))
  • PRL
  • peripheral blood monocytes
  • HUVEC cells
  • monocyte-derived dendritic cells
  • IFNL1
  • citarinostat
  • RPL13A
  • peripheral B lymphocytes
  • IFNA2

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • kinetochores

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human GPATCH11 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • kinetochore

Molecular Function

What the gene product does at the molecular level
  • nucleic acid binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.