TATDN2 Gene Summary [Human]
Predicted to enable metal ion binding activity and nuclease activity. Predicted to be involved in nucleic acid phosphodiester bond hydrolysis. Predicted to be located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TATDN2 |
| Official Name | TatD DNase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28988] |
| Ensembl ID | ENSG00000157014 |
| Bio databases IDs | |
| Aliases | TatD DNase domain containing 2 |
| Synonyms | LOC381801, mKIAA0218, TatD DNase domain containing 2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TATDN2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TatD related DNase
- hydrolase, TatD family
- metallo-dependent_hydrolases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TATDN2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- metal ion binding
- nuclease activity