Tatdn2 Gene Summary [Mouse]

Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and hemolymphoid system. Orthologous to human TATDN2 (TatD DNase domain containing 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Tatdn2
Official Name
TatD DNase domain containing 2 [Source:MGI Symbol;Acc:MGI:3576210]
Ensembl ID
ENSMUSG00000056952
Bio databases IDs NCBI: 381801 Ensembl: ENSMUSG00000056952
Aliases TatD DNase domain containing 2
Synonyms LOC381801, mKIAA0218, TatD DNase domain containing 2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tatdn2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • TatD related DNase
  • hydrolase, TatD family
  • metallo-dependent_hydrolases

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • gastric epithelial cancer
  • gastric carcinoma
  • chromosomal instability
regulated by
regulates
role in cell
  • survival
  • damage in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Tatdn2 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • metal ion binding
  • nuclease activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.