GPRASP2 Gene Summary [Human]

The protein encoded by this gene is a member of a family that regulates the activity of G protein-coupled receptors (GPCRs). The encoded protein has been shown to be capable of interacting with several GPCRs, including the M1 muscarinic acetylcholine receptor and the calcitonin receptor. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]

Details

Type
Protein Coding
Official Symbol
GPRASP2
Official Name
G protein-coupled receptor associated sorting protein 2 [Source:HGNC Symbol;Acc:HGNC:25169]
Ensembl ID
ENSG00000158301
Bio databases IDs NCBI: 114928 NCBI: 100528062 Ensembl: ENSG00000158301
Aliases G protein-coupled receptor associated sorting protein 2
Synonyms 5330440H13RIK, DFNX7, GASP-2, G protein-coupled receptor associated sorting protein 2, Prpl5, RGD1561019
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GPRASP2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-protein-coupled receptor binding
  • protein binding
  • beta-amyloid binding
  • Armadillo-like

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • endometrial cancer
  • X-linked deafness type 7
  • weight gain
regulated by
regulates
role in cell
  • abnormal morphology
  • excitatory postsynaptic potential
  • homeostasis
  • long term synaptic depression

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus
  • Plasma Membrane
  • neurites

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human GPRASP2 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • G-protein coupled receptor binding
  • protein binding
  • beta-amyloid binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.