ZER1 Gene Summary [Human]

This gene encodes a subunit of an E3 ubiquitin ligase complex that may be involved in meiosis. The encoded protein contains three leucine-rich repeat motifs. [provided by RefSeq, Nov 2012]

Details

Type
Protein Coding
Official Symbol
ZER1
Official Name
zyg-11 related cell cycle regulator [Source:HGNC Symbol;Acc:HGNC:30960]
Ensembl ID
ENSG00000160445
Bio databases IDs NCBI: 10444 Ensembl: ENSG00000160445
Aliases zyg-11 related cell cycle regulator
Synonyms C230075L19Rik, C9orf60, RGD1310284, ZYG, ZYG11BL, zyg-11 related cell cycle regulator, zyg-11 related, cell cycle regulator
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZER1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • myopia
regulated by
  • topotecan
  • Myb
  • v-Myb

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human ZER1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • misfolded or incompletely synthesized protein catabolic process
  • positive regulation of proteasomal ubiquitin-dependent protein catabolic process

Cellular Component

Where in the cell the gene product is active
  • Cul2-RING ubiquitin ligase complex

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.