SYCE2 Gene Summary [Human]

The protein encoded by this gene is part of the synaptonemal complex formed between homologous chromosomes during meiotic prophase. The encoded protein associates with SYCP1 and SYCE1 and is found only where chromosome cores are synapsed. [provided by RefSeq, Dec 2012]

Details

Type
Protein Coding
Official Symbol
SYCE2
Official Name
synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411]
Ensembl ID
ENSG00000161860
Bio databases IDs NCBI: 256126 Ensembl: ENSG00000161860
Aliases synaptonemal complex central element protein 2, central element synaptonemal complex 1
Synonyms 1700013H19Rik, CESC1, RGD1311867, synaptonemal complex central element protein 2
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SYCE2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • MYC mutation positive B-cell lymphoma
  • lymphomagenesis
  • B cell cancer
regulated by
role in cell
  • synapsis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • chromosome
  • nucleoplasm
  • synaptonemal complexes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human SYCE2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell division
  • synaptonemal complex assembly

Cellular Component

Where in the cell the gene product is active
  • central element
  • chromosome
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.