RBP7 Gene Summary [Human]

The protein encoded by this gene is a member of the cellular retinol-binding protein (CRBP) family, whose members are required for vitamin A stability and metabolism. The encoded protein binds all-trans-retinol and is structurally similar to other CRBPs; however, it has a lower binding affinity for retinol than other CRBPs. [provided by RefSeq, Aug 2016]

Details

Type
Nonsense Mediated Decay
Official Symbol
RBP7
Official Name
retinol binding protein 7 [Source:HGNC Symbol;Acc:HGNC:30316]
Ensembl ID
ENSG00000162444
Bio databases IDs NCBI: 116362 Ensembl: ENSG00000162444
Aliases retinol binding protein 7, cellular retinol binding protein 7
Synonyms 1110002J23Rik, CRABP4, CRBP4, CRBP-III, CRBPIV, retinol binding protein 7, retinol binding protein 7, cellular, RGD1562168
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RBP7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • lipocalin/cytosolic fatty acid-binding protein family
  • protein binding
  • retinoid binding
  • Lipocalin / cytosolic fatty-acid binding protein family

Pathways

Biological processes and signaling networks where the RBP7 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • peritoneal endometriosis
  • Ullrich congenital muscular dystrophy
  • systemic juvenile idiopathic arthritis
  • facioscapulohumeral muscular dystrophy type 2
regulated by
regulates
  • RBP1
  • retinyl palmitate
  • retinyl ester

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human RBP7 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • fatty acid transport

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • fatty acid binding
  • retinal binding
  • retinol binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.