YY1AP1 Gene Summary [Human]

Predicted to enable transcription coregulator activity. Involved in cell differentiation; cell population proliferation; and regulation of cell cycle. Located in fibrillar center and nucleoplasm. Colocalizes with Ino80 complex. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
YY1AP1
Official Name
YY1 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:30935]
Ensembl ID
ENSG00000163374
Bio databases IDs NCBI: 55249 Ensembl: ENSG00000163374
Aliases YY1 associated protein 1
Synonyms GRNG, HCCA1, HCCA2, Yap65, YY1AP, YY1 associated protein 1
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human YY1AP1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • neoplasia
  • Grange syndrome
  • mental retardation
regulated by
regulates
  • synthetic promoter
  • reporter gene
  • NF2
  • LATS
  • YY1
role in cell
  • differentiation
  • apoptosis
  • proliferation
  • colony formation
  • cell viability
  • growth
  • cell cycle progression

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • fibrillar center
  • Cytoplasm
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human YY1AP1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell proliferation
  • cell differentiation
  • regulation of transcription, DNA-dependent
  • regulation of cell cycle

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • Ino80 complex
  • nucleolus
  • fibrillar center
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • transcription cofactor activity
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.