TMEM68 Gene Summary [Human]

Predicted to enable acyltransferase activity. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Nonsense Mediated Decay
Official Symbol
TMEM68
Official Name
transmembrane protein 68 [Source:HGNC Symbol;Acc:HGNC:26510]
Ensembl ID
ENSG00000167904
Bio databases IDs NCBI: 137695 Ensembl: ENSG00000167904
Aliases transmembrane protein 68
Synonyms 2010300G19Rik, DIESL, MGAT/DGAT, RGD1309006, transmembrane protein 68
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMEM68 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis
  • phospholipid:diacylglycerol acyltransferase
  • enzyme
  • Acyltransferase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
  • triacylglycerol
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • endoplasmic reticulum membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human TMEM68 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • triglyceride biosynthetic process

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • membrane

Molecular Function

What the gene product does at the molecular level
  • phospholipid:diacylglycerol acyltransferase activity

Gene-Specific Assays for Results You Can Trust

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