Tmem68 Gene Summary [Mouse]
Predicted to enable phospholipid:diacylglycerol acyltransferase activity. Predicted to be involved in triglyceride biosynthetic process. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including genitourinary system. Orthologous to human TMEM68 (transmembrane protein 68). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Tmem68 |
| Official Name | transmembrane protein 68 [Source:MGI Symbol;Acc:MGI:1919348] |
| Ensembl ID | ENSMUSG00000028232 |
| Bio databases IDs | |
| Aliases | transmembrane protein 68 |
| Synonyms | 2010300G19Rik, DIESL, MGAT/DGAT, RGD1309006, transmembrane protein 68 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmem68 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis
- phospholipid:diacylglycerol acyltransferase
- enzyme
- Acyltransferase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmem68 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- triglyceride biosynthetic process
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- membrane
Molecular Function
What the gene product does at the molecular level
- phospholipid:diacylglycerol acyltransferase activity