ZNF282 Gene Summary [Human]
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ZNF282 |
| Official Name | zinc finger protein 282 [Source:HGNC Symbol;Acc:HGNC:13076] |
| Ensembl ID | ENSG00000170265 |
| Bio databases IDs | |
| Aliases | zinc finger protein 282 |
| Synonyms | E430019K09Rik, HUB1, Zfp282, zinc finger protein 282 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZNF282 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc finger, C2H2 type
- krueppel associated box
- zinc finger
- transcription regulator
- double-stranded DNA binding
- Zinc-finger double domain
- protein binding
- KRAB (Kruppel-associated box) domain -A box
- sequence-specific DNA binding
- C2H2-type zinc finger
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZNF282 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of transcription, DNA-dependent
- regulation of transcription, DNA-dependent
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- sequence-specific DNA binding transcription factor activity
- protein binding