FEZ2 Gene Summary [Human]
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Other orthologs include the rat gene that encodes zygin II, which can bind to synaptotagmin. [provided by RefSeq, Jul 2008]
Details
| Type | Processed Transcript |
| Official Symbol | FEZ2 |
| Official Name | fasciculation and elongation protein zeta 2 [Source:HGNC Symbol;Acc:HGNC:3660] |
| Ensembl ID | ENSG00000171055 |
| Bio databases IDs | |
| Aliases | fasciculation and elongation protein zeta 2, zygin II |
| Synonyms | 3C1, 9030616F16, D17Ertd315e, fasciculation and elongation protein zeta 2, fasciculation and elongation protein ζ 2, HUM3CL, ZRP |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human FEZ2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- FEZ-like protein
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human FEZ2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- signal transduction
- nervous system development
- axon guidance
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- axon
Molecular Function
What the gene product does at the molecular level
- protein binding