Fez2 Gene Summary [Mouse]
Predicted to be involved in negative regulation of autophagosome assembly. Predicted to be active in axon and cytoplasm. Is expressed in embryo. Orthologous to human FEZ2 (fasciculation and elongation protein zeta 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fez2 |
| Official Name | fasciculation and elongation protein zeta 2 (zygin II) [Source:MGI Symbol;Acc:MGI:2675856] |
| Ensembl ID | ENSMUSG00000056121 |
| Bio databases IDs | |
| Aliases | fasciculation and elongation protein zeta 2 (zygin II) |
| Synonyms | 3C1, 9030616F16, D17Ertd315e, fasciculation and elongation protein zeta 2, fasciculation and elongation protein ζ 2, HUM3CL, ZRP |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fez2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- FEZ-like protein
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Fez2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- signal transduction
- nervous system development
- axon guidance
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- axon
Molecular Function
What the gene product does at the molecular level
- protein binding