UFSP1 Gene Summary [Human]
This gene encodes a protein that is similar to other Ufm1-specific proteases. Studies in mouse determined that Ufsp1 releases Ufm1 (ubiquitin-fold modifier 1) from its bound conjugated complexes which also makes it into an active form. Because the human UFSP1 protein is shorter on the N-terminus and lacks a conserved Cys active site, it is predicted to be non-functional.[provided by RefSeq, Nov 2009]
Details
| Type | Protein Coding |
| Official Symbol | UFSP1 |
| Official Name | UFM1 specific peptidase 1 (inactive) [Source:HGNC Symbol;Acc:HGNC:33821] |
| Ensembl ID | ENSG00000176125 |
| Bio databases IDs | |
| Aliases | UFM1 specific peptidase 1 (inactive) |
| Synonyms | 2700038N03Rik, D5Ertd655e, UFM1-specific peptidase 1, UFSP |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human UFSP1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cysteine-type peptidase
- Peptidase family C78
- enzyme
- protein binding
- ubiquitin-like-specific protease
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human UFSP1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein maturation
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- UFM1 hydrolase activity
- cysteine-type peptidase activity