ZFAS1 Gene Summary [Human]
This gene represents a snoRNA host gene that produces a non-coding RNA. Increased expression or amplification of this locus is associated with cancer progression and metastasis. This transcript regulates expression of genes involved in differentiation. It may act a molecular sponge for microRNAs. Alternatively spliced transcript variants have been observed. [provided by RefSeq, Dec 2017]
Details
| Type | Long Non-Coding RNA |
| Official Symbol | ZFAS1 |
| Official Name | ZNFX1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:33101] |
| Ensembl ID | ENSG00000177410 |
| Bio databases IDs | |
| Aliases | ZNFX1 antisense RNA 1 |
| Synonyms | C20orf199, HSUP1, HSUP2, NCRNA00275, ZNFX1 antisense RNA 1, ZNFX1-AS1 |
| Species | Human, Homo sapiens |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- organismal death
- gastric carcinoma
- gastric epithelial cancer
- osteosarcoma
- osteosarcomagenesis
- metastasis
- bladder cancer
- colorectal cancer
- insomnia
role in cell
- expression in
- proliferation
- apoptosis
- production in
- Gap 0-Gap 1 phase
- migration
- invasion by
- epithelial-mesenchymal transition in
- G0/G1 phase transition
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZFAS1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm