CSTF2T Gene Summary [Human]
Enables RNA binding activity. Predicted to be involved in pre-mRNA cleavage required for polyadenylation. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CSTF2T |
| Official Name | cleavage stimulation factor subunit 2 tau variant [Source:HGNC Symbol;Acc:HGNC:17086] |
| Ensembl ID | ENSG00000177613 |
| Bio databases IDs | |
| Aliases | cleavage stimulation factor subunit 2 tau variant |
| Synonyms | cleavage stimulation factor, 3' pre-RNA subunit 2, tau, cleavage stimulation factor subunit 2 tau variant, cleavage stimulation factor subunit 2, tau variant, CstF-64T, KIAA0689, tauCstF-64, tCstF-64 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CSTF2T often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Transcription termination and cleavage factor C-terminal
- Hinge domain of cleavage stimulation factor subunit 2
- RNA recognition motif (RRM) superfamily
- RNA recognition motif
- protein binding
- RNA binding
Pathways
Biological processes and signaling networks where the CSTF2T gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- intracellular membrane-bounded organelle
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CSTF2T gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mRNA 3'-end processing
Cellular Component
Where in the cell the gene product is active
- mRNA cleavage and polyadenylation specificity factor complex
- intracellular membrane-bounded organelle
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- mRNA binding