FNDC3A Gene Summary [Human]
Enables RNA binding activity. Predicted to act upstream of or within several processes, including Sertoli cell development; fertilization; and spermatid development. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | FNDC3A |
| Official Name | fibronectin type III domain containing 3A [Source:HGNC Symbol;Acc:HGNC:20296] |
| Ensembl ID | ENSG00000102531 |
| Bio databases IDs | |
| Aliases | fibronectin type III domain containing 3A |
| Synonyms | 1700094E19Rik, bA203I16.1, bA203I16.5, D14Ertd453e, F730017H24Rik, Fibronectin Type III Domain Containing 3, fibronectin type III domain containing 3A, FND3A, FNDC3, HUGO, KIAA0970, sys |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human FNDC3A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- FN3
- Purple acid Phosphatase, N-terminal domain
- Fibronectin type 3 domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- insomnia
- Crohn disease
- uterine leiomyoma
- leiomyomatosis
- inflammatory bowel disease
- myasthenia gravis
- hypogonadotropic hypogonadism
regulates
role in cell
- apoptosis
- development
- transcription in
- accumulation in
- fertilization
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
- cytosol
- vesicle membrane
- acrosome
- cytoplasmic vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human FNDC3A gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spermatid development
- fertilization
- Sertoli cell development
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- vesicle membrane
- intracellular membrane-bounded organelle
- acrosomal vesicle
- membrane
- cytosol
- Golgi membrane
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- RNA binding