TNRC18 Gene Summary [Human]

Predicted to enable chromatin binding activity. Located in cytosol; mitochondrion; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
TNRC18
Official Name
trinucleotide repeat containing 18 [Source:HGNC Symbol;Acc:HGNC:11962]
Ensembl ID
ENSG00000182095
Bio databases IDs NCBI: 84629 Ensembl: ENSG00000182095
Aliases trinucleotide repeat containing 18
Synonyms CAGL79, EG381742, KIAA1856, LOC285923, LOC679549, LOC679577, LOC686206, TNRC18A, trinucleotide repeat containing 18, Zfp469
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TNRC18 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • BAH
  • BAH domain
  • DNA repair protein Crb2 Tudor domain
  • Tudor domain superfamily

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • psoriasis
  • lichen planus
  • uveitis
  • oral lichen planus
  • prostate cancer
  • iritis
  • Wilms tumor
  • Wilms tumorigenesis
  • Crohn disease
  • ulcerative colitis
regulated by
  • GNE-987
regulates
role in cell
  • expression in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Mitochondria
  • cytosol
  • nucleoplasm
  • nuclear envelope

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human TNRC18 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • nuclear membrane
  • mitochondrion
  • cytosol
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • chromatin binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.