UBOX5 Gene Summary [Human]
This gene encodes a U-box domain containing protein. The encoded protein interacts with E2 enzymes and may play a role in the ubiquitination pathway. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Details
| Type | Protein Coding |
| Official Symbol | UBOX5 |
| Official Name | U-box domain containing 5 [Source:HGNC Symbol;Acc:HGNC:17777] |
| Ensembl ID | ENSG00000185019 |
| Bio databases IDs | |
| Aliases | U-box domain containing 5 |
| Synonyms | 1500010O06RIK, C330018L13Rik, hUIP5, RGD1305440, RNF37, UBCE7IP5, Ube7ip5, U-box domain containing 5, UIP5 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human UBOX5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ubiquitin protein ligase binding
- ubiquitin protein ligase activity
- RING finger (Really Interesting New Gene) domain and U-box domain superfamily
- Modified RING finger domain
- enzyme
- protein binding
- Family of unknown function (DUF5918)
- Zinc finger, C3HC4 type (RING finger)
- zinc-RING finger domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- focal adhesions
- nucleoplasm
- nuclear bodies
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human UBOX5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein polyubiquitination
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear body
- focal adhesion
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- ubiquitin protein ligase binding
- protein binding
- metal ion binding
- ubiquitin-ubiquitin ligase activity