KRT26 Gene Summary [Human]

The protein encoded by this gene is a member of the keratin superfamily. This keratin protein is a type I keratin that is specific for the inner root sheath of the hair follicle. This gene exists in a cluster with other keratin genes on chromosome 17q21. [provided by RefSeq, Jul 2009]

Details

Type
Protein Coding
Official Symbol
KRT26
Official Name
keratin 26 [Source:HGNC Symbol;Acc:HGNC:30840]
Ensembl ID
ENSG00000186393
Bio databases IDs NCBI: 353288 Ensembl: ENSG00000186393
Aliases keratin 26
Synonyms 4732407F15Rik, CK26, K25B, K25IRS2, K26, keratin 26, KRT25B
Species
Human, Homo sapiens
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human KRT26 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Intermediate filament protein

Pathways

Biological processes and signaling networks where the KRT26 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • androgenic alopecia
regulated by
  • tetradecanoylphorbol acetate
  • Gstp1 (includes others)

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human KRT26 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • epithelial cell differentiation
  • intermediate filament organization

Cellular Component

Where in the cell the gene product is active
  • cytoskeleton
  • extracellular vesicular exosome
  • cytosol
  • intermediate filament

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • structural molecule activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.