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Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. The type II keratins are clustered in a region of chromosome 12q13. [provided by RefSeq, Jun 2009]
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human KRT76 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
protein binding
Intermediate filament protein
Keratin type II head
Pathways
Biological processes and signaling networks where the KRT76 gene in human plays a role, providing insight into its function and relevance in health or disease.
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
Cytoplasm
cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human KRT76 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
cytoskeleton organization
pigmentation
sebaceous gland development
keratinization
intermediate filament organization
Cellular Component
Where in the cell the gene product is active
nucleus
keratin filament
extracellular vesicular exosome
cytosol
intermediate filament
Molecular Function
What the gene product does at the molecular level
structural constituent of epidermis
protein binding
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