LIN54 Gene Summary [Human]
LIN54 is a component of the LIN, or DREAM, complex, an essential regulator of cell cycle genes (Schmit et al., 2009 [PubMed 19725879]).[supplied by OMIM, Dec 2010]
Details
| Type | Processed Transcript |
| Official Symbol | LIN54 |
| Official Name | lin-54 DREAM MuvB core complex component [Source:HGNC Symbol;Acc:HGNC:25397] |
| Ensembl ID | ENSG00000189308 |
| Bio databases IDs | |
| Aliases | lin-54 DREAM MuvB core complex component, CXC domain containing 1 |
| Synonyms | CXCDC1, JC8.6, lin-54 DREAM MuvB core complex component, MIP120, RGD1311361, TCX1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LIN54 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- nucleic acid binding
- protein binding
- Tesmin/TSO1-like CXC domain, cysteine-rich domain
- AT DNA binding
- DNA-binding cysteine-rich domain of male-specific lethal 2 and related proteins
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human LIN54 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nucleosome organization
- regulation of transcription, DNA-dependent
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- regulatory region nucleic acid binding
- protein binding
- metal ion binding
- AT DNA binding