LIN54 Gene Summary [Mouse]
Predicted to enable minor groove of adenine-thymine-rich DNA binding activity and transcription regulatory region nucleic acid binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to act upstream of or within nucleosome organization. Predicted to be part of RNA polymerase II transcription repressor complex. Predicted to be active in nucleus. Orthologous to human LIN54 (lin-54 DREAM MuvB core complex component). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | LIN54 |
| Official Name | lin-54 homolog (C. elegans) [Source:NCBI gene (formerly Entrezgene);Acc:231506] |
| Ensembl ID | ENSMUSG00000118665 |
| Bio databases IDs | |
| Aliases | lin-54 homolog (C. elegans) |
| Synonyms | CXCDC1, JC8.6, lin-54 DREAM MuvB core complex component, MIP120, RGD1311361, TCX1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lin54 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- nucleic acid binding
- protein binding
- Tesmin/TSO1-like CXC domain, cysteine-rich domain
- AT DNA binding
- DNA-binding cysteine-rich domain of male-specific lethal 2 and related proteins
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Lin54 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nucleosome organization
- regulation of transcription, DNA-dependent
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- regulatory region nucleic acid binding
- protein binding
- metal ion binding
- AT DNA binding