ZSCAN25 Gene Summary [Human]

This gene encodes a protein that bears some similarity to zinc finger proteins, which are involved in DNA binding and protein-protein interactions. Multiple alternatively spliced transcript variants have been identified, but the full-length nature for most of them has not been determined. [provided by RefSeq, Jul 2008]

Details

Type
Retained Intron
Official Symbol
ZSCAN25
Official Name
zinc finger and SCAN domain containing 25 [Source:HGNC Symbol;Acc:HGNC:21961]
Ensembl ID
ENSG00000197037
Bio databases IDs NCBI: 221785 Ensembl: ENSG00000197037
Aliases zinc finger and SCAN domain containing 25
Synonyms EG666311, LOC103693617, Zfp498, zinc finger and SCAN domain containing 25, ZNF498
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZSCAN25 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Zinc finger, C2H2 type
  • leucine rich region
  • zinc finger
  • Zinc-finger double domain
  • SCAN domain
  • protein binding
  • C2H2-type zinc finger

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • neoplasia
  • hepatocellular carcinoma
  • epithelial cancer
  • organismal death
  • liver cancer
regulated by
role in cell
  • apoptosis
  • proliferation
  • expression in
  • binding in
  • ferroptosis
  • phosphorylation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human ZSCAN25 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of transcription from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • nucleus

Molecular Function

What the gene product does at the molecular level
  • metal ion binding
  • RNA polymerase II core promoter proximal region sequence-specific DNA binding
  • sequence-specific DNA binding RNA polymerase II transcription factor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.