STYX Gene Summary [Human]
The protein encoded by this gene is a pseudophosphatase, able to bind potential substrates but lacking an active catalytic loop. The encoded protein may be involved in spermiogenesis. Two transcript variants encoding the same protein have been found for these genes. [provided by RefSeq, Oct 2011]
Details
| Type | Protein Coding |
| Official Symbol | STYX |
| Official Name | serine/threonine/tyrosine interacting protein [Source:HGNC Symbol;Acc:HGNC:11447] |
| Ensembl ID | ENSG00000198252 |
| Bio databases IDs | |
| Aliases | serine/threonine/tyrosine interacting protein |
| Synonyms | 0610039A20Rik, hStyxb, LOC730432, serine/threonine/tyrosine interacting protein, serine/threonine/tyrosine interaction protein, STYXB |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human STYX often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Dual specificity phosphatase, catalytic domain
- Protein tyrosine phosphatase, catalytic domain, undefined specificity
- pseudophosphatase
- phosphatase
- protein domain specific binding
- protein binding
- PTP_DSP_cys
- Protein tyrosine phosphatase, catalytic domain motif
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- asthenozoospermia
role in cell
- development
- differentiation
- binding in
- migration
- abnormal morphology
- morphology
- production
- polarization
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- perinuclear region
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human STYX gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of ERK1 and ERK2 cascade
- negative regulation of protein binding
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- pseudophosphatase activity